Dr. Ke Xu is a physician scientist studying human addiction genetics and epigenetics. She completed her postdoc training at National Institute of Alcohol Abuse and Alcoholism and the residency training in psychiatry at Yale NRTP. Her research has focused on understanding how substance use and misuse impact human epigenome and transcriptome in the context of HIV infection. Her research goal is to apply computational methods to translate genomic features to clinic use.
What do you do with data science?
Our work has focused on applying computational models predicting substance misuse related clinic outcomes. We used machine and deep learning methods to select DNA methylation features predicting alcohol and drug misuse related frailty and mortality risks. Our work also involves predicting medication treatment response in psychiatric disorders by applying computational genomics methods. We participated three DREAM BioMedical Challenges and received top ranked awards.